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A new Northwestern study shows that RNA interference may play a key role in Alzheimer’s. For the first time, scientists have identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer’s and aged brains. Short strands of protective RNAs are decreased during aging which may allow Alzheimer’s to develop.
Alzheimer’s disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells. But the events that cause neuron death are poorly understood.A new Northwestern Medicine study shows
Alzheimer's disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells.
<p style="text-align:start">The cause of neuron death in Alzheimer’s disease is poorly understood. A new study shows RNA interference may play a key role. Scientists have identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer’s and aged brains. Increasing protective short RNAs may be new approach to halt or delay Alzheimer’s. The study also found that older individuals with a superior memory capacity (known as SuperAgers) have higher amounts of protective short RNA strands in their b...
Interestingly, SuperAgers, older individuals with exceptional memory, possess higher levels of protective sRNAs.