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Researchers induced a hibernation-like state in mice by using ultrasound to stimulate the hypothalamus preoptic area in the brain, which helps to regulate body temperature and metabolism. The findings show the first noninvasive and safe method to induce such a state; a similar condition has been previously proposed for spaceflight or for patients with life-threatening health conditions.

A groundbreaking study published in Nature Metabolism has unveiled a noninvasive and safe method to induce a torpor-like state in mice and rats. Led by

Some mammals and birds have a clever way to preserve energy and heat by going into torpor, during which their body temperature and metabolic rate drop. Researchers at Washington University in St. Louis safely and noninvasively induced a torpor-like state in mice and rats by using ultrasound to stimulate the hypothalamus preoptic area in the brain.