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Suspended Animation for Space Travel May Come from Ultrasound

‘Suspended animation’ has enabled more science fiction movie and novel plots than artificial gravity, laser guns ....

Hong Chen , Vladyslav Vyazovskiy , Yaoheng Mack Yang , Washington University In St , Oxford University , Washington University , Nature Metabolism , Live Science ,

Induction of a torpor-like state with ultrasound: Chen's team used ultrasound to safely, noninvasively induce a torpor-like state in mice, rats

Researchers induced a hibernation-like state in mice by using ultrasound to stimulate the hypothalamus preoptic area in the brain, which helps to regulate body temperature and metabolism. The findings show the first noninvasive and safe method to induce such a state; a similar condition has been previously proposed for spaceflight or for patients with life-threatening health conditions. ....

Michaelr Bruchas , Hong Chen , Jianmin Cui , Jonathanr Brestoff , Yaoheng Mack Yang , Alexxaiv Kravitz , School Of Medicine , Mckelvey School Of Engineering , University Of Washington , Washington University In St , Washington University , Nature Metabolism , Mckelvey School ,

Induction of a torpor-like state with ultrasound - The Source - Washington University in St. Louis

Some mammals and birds have a clever way to preserve energy and heat by going into torpor, during which their body temperature and metabolic rate drop. Researchers at Washington University in St. Louis safely and noninvasively induced a torpor-like state in mice and rats by using ultrasound to stimulate the hypothalamus preoptic area in the brain. ....

Michaelr Bruchas , Yaoheng Mack Yang , Hong Chen , Alexxaiv Kravitz , Jonathanr Brestoff , Jianmin Cui , Mckelvey School Of Engineering , School Of Medicine , Washington University In St , University Of Washington , Washington University , Nature Metabolism , Mckelvey School ,

Static magnetic field from MRI scanner decreases blood-brain barrier opening volume


Static magnetic field from MRI scanner decreases blood-brain barrier opening volume
MRI-guided focused ultrasound combined with microbubbles can open the blood-brain barrier (BBB) and allow therapeutic drugs to reach the diseased brain location under the guidance of MRI. It is a promising technique that has been shown safe in patients with various brain diseases, such as Alzheimer s diseases, Parkinson s disease, ALS, and glioblastoma. While MRI has been commonly used for treatment guidance and assessment in preclinical research and clinical studies, until now, researchers did not know the impact of the static magnetic field generated by the MRI scanner on the BBB opening size and drug delivery efficiency. ....

Hong Chen , Yaoheng Mack Yang , Emily Henderson , School Of Medicine , Mckelvey School Of Engineering , Washington University In St Louis , Washington University In St , Washington University , Mckelvey School , Study Lead Author , Doctoral Student , ஹாங் சென் , எமிலி ஹென்டர்சன் , பள்ளி ஆஃப் மருந்து , ம்க்கெல்வேய் பள்ளி ஆஃப் பொறியியல் , வாஷிங்டன் பல்கலைக்கழகம் இல் ஸ்டம்ப் லூயிஸ் , வாஷிங்டன் பல்கலைக்கழகம் இல் ஸ்டம்ப் , வாஷிங்டன் பல்கலைக்கழகம் , ம்க்கெல்வேய் பள்ளி , படிப்பு வழி நடத்து நூலாசிரியர் , முனைவர் மாணவர் ,