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President Biden calls it 'a win for American workers and the American auto industry.'

Date Time Hormones in brain may explain how exercise improves metabolism A collaboration between the USC Leonard Davis School of Gerontology and researchers in South Korea has shown how moderate exercise prompts cells in the hypothalamus, the small region within the brain that controls metabolism, to release a hormone called MOTS-c. MOTS-c is a small protein that is encoded in cells’ smaller mitochondrial genome, rather than the larger collection of genes in the nucleus, said Changhan David Lee, assistant professor of gerontology at the USC Leonard Davis School and co-senior author of the n...

Credit: Stephanie Kleinman/USC A mitochondrial hormone expressed by cells deep in the brain appears to play a role in improving metabolism and fighting off obesity, according to a new study in mice. A collaboration between the USC Leonard Davis School of Gerontology and researchers in South Korea has shown how moderate exercise prompts cells in the hypothalamus, the small region within the brain that controls metabolism, to release a hormone called MOTS-c. MOTS-c is a small protein that is encoded in cells' smaller mitochondrial genome, rather than the larger collection of genes in the nucleu...

Credit: Khademhosseini Lab (LOS ANGELES) - There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins." These checkpoint proteins bind to proteins on the surface of other cells and can result in either stimulation or suppression of T-cell activity. Normally, surface proteins on foreign or invading cells will produce a stimulation of T-cell activity against these cells, while T-cell suppression is a built-in mechanism to prevent the im...

Screening for endocrine disruption in artificial zebrafish for long-term risk assessment Newly developed chemical substances or cosmetics can be distributed only after passing the risk assessment in human and environment. The developed product distribution is prohibited if it cannot pass the safety assessment for endocrine disruption, such as bisphenol A (BPA), removed from the market. The toxicity assessment of EDCs in the environmental aspect generally requires OECD testing on three species: Daphnia pulex, green algae, and zebrafish. Especially zebrafish is that similar to more than 90% hum...