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Princeton cancer researchers Mark Esposito and Yibin Kang discovered a new, still-unnamed organelle that plays a role in bone metastasis and is formed via liquid-liquid phase separation — when liquid blobs of living materials merge into each other. “We believe this is the first time that phase separation has been implicated in cancer metastasis,” said Kang.
Cell mapping expert receives HHMI diversity fellowship with eight years of support Scott Lyon, Office of Engineering Communications Feb. 18, 2021 1 p.m. The Howard Hughes Medical Institute (HHMI) has named Princeton postdoctoral researcher Sofia Quinodoz a 2020 Hanna Gray Fellow, bolstering her study into how the structures within cells contribute to disease. Quinodoz will receive up to $1.4 million over the next eight years, funding her bioengineering research at Princeton and granting her startup funds for an unspecified future role as a principal investigator. Quinodoz, whose fa...
A new view of biology January 26, 2021Princeton Cliff Brangwynne was seeing cells in the sidewalk again. It was another long day in the lab at Harvard Medical School, where Brangwynne would often work late nights, staring at cells. Sometimes he spent so much time staring at cells through the microscope that the cells would follow him home, their shapes imprinted on his vision. Walking late at night, he’d see them dancing over the buildings and the empty streets and sidewalks. Though Brangwynne was in his college years, he wasn’t a student — in fact, some would call him a dropout. He...
Cliff Brangwynne upends tradition to establish a new view of biology Jerimiah Oetting, for the Office of the Dean for Research Jan. 25, 2021 9 a.m. Clifford Brangwynne, the June K. Wu ’92 Professor of Chemical and Biological Engineering and inaugural director of the Princeton Bioengineering Initiative, sees similarities between living cells and salad dressing, in which oil and vinegar separate according to the laws of physics. The idea has caught on, and now many scientists are exploring how such physical processes can drive the formation of the cell’s structures and play ...