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The Toolmaker's Mind | Princeton Alumni Weekly

Photo: © John D. and Catherine T. MacArthur Foundation — used with permission
features
The Toolmaker’s Mind
Clifford Brangwynne marries engineering and biology in a quest to understand the inner workings of the cell
Photo: © John D. and Catherine T. MacArthur Foundation — used with permission
By Carmen Drahl *07
The best way to learn how intensely Princeton bioengineer Clifford P. Brangwynne approaches life is to catch him playing hockey at Baker Rink. Before the COVID-19 pandemic, he had a standing noontime game. He’s played since childhood, mostly defense. At Baker, he might be fending off collaborator and friend Mikko Haataja, a professor of mechanical and aerospace engineering at Princeton and a formidable forward. “When you play intense sports, that’s the only thing that’s consciously on your mind,” Brangwynne says. With skates on, he gets in the zone. And when Cliff Brangwynne gets in the zone, there’s no stopping him.

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A new view of biology - ScienceBlog.com

A new view of biology
January 26, 2021Princeton
Cliff Brangwynne was seeing cells in the sidewalk again.
It was another long day in the lab at Harvard Medical School, where Brangwynne would often work late nights, staring at cells. Sometimes he spent so much time staring at cells through the microscope that the cells would follow him home, their shapes imprinted on his vision. Walking late at night, he’d see them dancing over the buildings and the empty streets and sidewalks.
Though Brangwynne was in his college years, he wasn’t a student — in fact, some would call him a dropout. He’d been enrolled at Carnegie Mellon University, a ﬁrst-generation college student, when a mixture of burnout and wanderlust prompted him to take a year off midway through his degree. At ﬁrst he thought he would take a yearlong trip to Latin America. But he was interested in materials science — he liked how it described the world in terms of math and physics. He also loved biology: he loved that innumerable cells could self-assemble into organisms that eventually walk around and talk about philosophy.

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Cliff Brangwynne upends tradition to establish a new view of biology

Cliff Brangwynne upends tradition to establish a new view of biology
Jerimiah Oetting, for the Office of the Dean for Research
Jan. 25, 2021 9 a.m.
Clifford Brangwynne, the June K. Wu ’92 Professor of Chemical and Biological Engineering and inaugural director of the Princeton Bioengineering Initiative, sees similarities between living cells and salad dressing, in which oil and vinegar separate according to the laws of physics. The idea has caught on, and now many scientists are exploring how such physical processes can drive the formation of the cell’s structures and play key roles in cellular division and gene expression.
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