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With a $2 million National Institutes of Health (NIH) grant, Matthew Lew in the McKelvey School of Engineering at Washington University in St. Louis will develop smart microscopes to reveal dynamic interactions between individual biomolecules.
A new multidisciplinary center focused on biomolecular condensates — distinct molecular communities that make up the building blocks of life — has launched at the McKelvey School of Engineering at Washington University in St. Louis.
New research led by Kiersten Ruff, a senior research scientist in the lab of Rohit Pappu at the McKelvey School of Engineering, has uncovered the rules that govern how unfolded proteins are identified — and found that exceptions to the rules may play a role in dysfunctional cells.
Every cell contains millions of protein molecules. Some of them have the ability to phase-separate to form non-membrane-bound compartments, called biomolecular condensates, inside a cell. It has long been assumed that there was no further structure u
A research group led by Rohit Pappu in the McKelvey School of Engineering at Washington University in St. Louis and Anthony Hyman at the Max Planck Institute have discovered a new, relevant level of structure in cells.