Cells sense and respond to the mechanical properties of the cellular microenvironment in the body. Changes in these properties, which occur in a number of human pathologies, including cancer, can elicit abnormal responses from cells.
Washington [US], May 26 (ANI): Cells sense and respond to the mechanical properties of the cellular microenvironment in the body. Changes in these properties, which occur in a number of human pathologies, including cancer, can elicit abnormal responses from cells but how the cells adapt to such changes in the mechanical microenvironment is not well understood.
Cells sense and respond to the mechanical properties of the cellular microenvironment in the body. Changes in these properties, which occur in a number of human
An interdisciplinary team seeks to better understand how the mechanical properties of cells operate in the body and how pathologies can disrupt these processes.
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Cells sense and respond to the mechanical properties of the cellular microenvironment in the body. Changes in these properties, which occur in a number of human pathologies, including cancer, can elicit abnormal responses from cells. How the cells adapt to such changes in the mechanical microenvironment is not well understood.
A team of researchers at Texas A&M University is working to understand cellular mechanosensing the ability to sense and respond to the mechanical properties of the microenvironment in a unique way. Tanmay Lele, Unocal Professor in the Department of Biomedical Engineering, Department of Chemical Engineering and the Department of Translational Medical Sciences, partnered with Charles Baer, an evolutionary biologist at the University of Florida. Together they used methods of experimental cellular evolution as a means to understand cellular adaptation to biomaterials of controlled mechanical properties.