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<p>For many genetic diseases, disabling or editing a gene using CRISPR is insufficient to overcome the effects of the underlying genetic mutation. A corrective gene needs to be added to the genome to fix the problem. UC Berkeley researchers have discovered a way to use a bird retrotransposon — a type of junk DNA — to insert whole transgenes into the human genome in a targeted way that does not risk damaging other genes.</p> ....
The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease. ....
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