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Math Model Exploits Cancer Cell Plasticity for Therapy Dosing

Math Model Exploits Cancer Cell Plasticity for Therapy Dosing
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South Korea , Kim Eunjung , Natural Products Informatics Research Center , Korea Institute Of Science , Korea Institute , Director Oh Sangrok ,

Mathematical Model Driven Evolutionary Therapy Dos

A research team led by Dr. Kim Eunjung at the Natural Products Informatics Research Center of the Korea Institute of Science and Technology (KIST) has esta ....

South Korea , Kim Eunjung , Natural Products Informatics Research Center , Korea Institute Of Science , Ministry Of Science , Korea Institute , Director Oh Sangrok , Minister Lee Jong Ho ,

Researchers develop mathematical model to predict effective dosage range of cancer treatment

Cancer poses significant challenges due to the development of resistance and the likelihood of relapse. Resistance may arise from permanent genetic changes in cancer cells or non-genetic alterations in cancer cell behavior induced by treatment. ....

South Korea , Kim Eunjung , Korea Institute Of Science , National Research Council Of Science Technology , Ministry Of Science , Natural Products Informatics Research Center , Research Council , Korea Institute , Director Oh Sangrok , Minister Lee Jong Ho ,

Mathematical model exploits cancer cell plasticity to guide adaptive therapy

Cancer poses significant challenges due to the development of resistance and the likelihood of relapse. Resistance may arise from permanent genetic changes in cancer cells or non-genetic alterations in cancer cell behavior induced by treatment. Standard of care in cancer treatments typically involves administering the maximum tolerated dose of a drug to eradicate drug-sensitive cells effectively. However, this approach often fails in the long term because drug-resistant cancer cells can grow more rapidly when all drug-sensitive cancer cells are killed off. ....

South Korea , Kim Eunjung , Korea Institute Of Science , Natural Products Informatics Research Center , Korea Institute ,