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Scientists develop a rapid gene-editing screen to find effects of cancer mutations

MIT researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing.

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CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

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Gene-editing technique could speed up study of cancer mutations

In an advance that could help scientists learn more about cancer-linked mutations whose roles are not known, MIT researchers have developed a way to easily engineer specific cancer-linked mutations into mouse models, using CRISPR prime editing.

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New tool reveals how immune cells find their targets

The human body has millions of unique B and T cells that roam the body, looking for microbial invaders. These immune cells’ ability to recognize harmful

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New tool reveals how immune cells find their targets

MIT biological engineers have devised a new experimental tool that allows them to precisely pick out interactions between a particular B or T cell and its target antigen.

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