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Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma


Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma
In people with central nervous system (CNS) lymphoma, cancerous B cells a type of white blood cell accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels. This disease is quite rare, but individuals who are affected have limited treatment options and often experience recurrence.
Previous research has linked the severity of CNS lymphoma to abnormal leaks in the blood-brain barrier, a protective system that allows some substances to pass from the bloodstream to the brain, while blocking others. However, the specific molecular details of this link have been murky. ....

United States , Katerina Akassoglou , Justin Chan , James Rubenstein , Emily Henderson , University Of California , School Of Medicine , Helen Diller Family Comprehensive Cancer Center , Staff Research Scientist , Kyu Ryu , Senior Author , American Journal , Diller Family Comprehensive Cancer Center , Neurovascular Brain , Neurovascular Brain Immunology , Central Nervous System , Nervous System , Blood Vessels , Cns Lymphoma , White Blood Cell , ஒன்றுபட்டது மாநிலங்களில் , ஜஸ்டின் சான் , ஜேம்ஸ் ரூபன்ஸ்டீன் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , பள்ளி ஆஃப் மருந்து ,