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Frontiers | The fecal microbiota from children with autism impact gut metabolism and learning and memory abilities of honeybees

Frontiers | The fecal microbiota from children with autism impact gut metabolism and learning and memory abilities of honeybees
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Insights Into Animal Well-Being via PhenoTyper

This article outlines the welfare that should be used in research with animal models such as mice. This article contains information on housing strategies for mice and the insights into animal well-being provided by PhenoTyper. ....

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Frontiers | A Smartphone App for Individual Xylazine/Ketamine Calculation Decreased Anesthesia-Related Mortality in Mice

2Laboratory of Cell Signaling, Obesity and Comorbidities Research Center, University of Campinas, Campinas, Brazil
3Faculty of Medical Sciences, University of Campinas, Campinas, Brazil
4Laboratory of Digital Signal Processing in Real Time, School of Electrical and Computer Engineering, University of Campinas, Campinas, Brazil
5Department of Chemical and Biomolecular Engineering, University of Nebraska, Lincoln, NE, United States
Currently, experimental animals are widely used in biological and medical research. However, the scientific community has raised several bioethical concerns, such as the number of animals required to achieve reproducible and statistically relevant results. These concerns involve aspects related to pain, discomfort, and unwanted animal loss. Retrospectively, we compare two different approaches for anesthesia dosage: a mobile app for dose calculation and a standard dose calculation. A total of 939 C57BL/6J and Swiss mice were analyzed. We co ....

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