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Immunological responses against monkeypox virus concerning the 2022 outbreak

A new study aimed to analyze the kinetics of the pox-specific T-cell induction, the inflammatory profile, and the inflammatory profile in human cases of the current monkeypox outbreak. ....

Lab Diagnostics Automation , Lab Diagnostics Automation Industry , Automation Industry Focus , Image Credit , Lancet Infectious Diseases , Immune Response , T Cell ,

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

Researchers used a deep antibody-antigen interaction (DeepAAI) algorithm to understand the antibody representations of unseen antibodies to accelerate the discovery of novel antibodies with potential therapeutic applications. ....

Lab Diagnostics Automation , Lab Diagnostics Automation Industry , Nature Machine Intelligence , Corona Borealis , Automation Industry Focus , Image Credit , Immune Response , Ars Cov 2 ,

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method. ....

Aimee Molineux , Neha Mathurnov , Neha Mathur , Research Collaboratory , Protein Data Bank , Lab Diagnostics Automation , University Of Arizona , Lab Diagnostics Automation Industry , Automation Industry Focus , Structural Bioinformatics , Coronavirus Disease Covid 19 , Ars Cov 2 , N Vitro , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Researchers use lasso-grafting for designing receptor agonists with enhanced pharmacokinetics

Cell growth and repair are stimulated by biomolecules known as cytokines and growth factors. Unfortunately, delivering adequate concentrations of these molecules to the brain for treating neurological conditions like Alzheimer's disease is challenging as they are either cleared out of the blood very quickly or do not penetrate neural tissue effectively. ....

Kunio Matsumoto , Hiroaki Suga , Emily Henderson , University Of Tokyo , Lab Diagnostics Automation , Lab Diagnostics Automation Industry , Junichi Takagi At Osaka University , Katsuya Sakai At Kanazawa University , Junichi Takagi , Osaka University , Katsuya Sakai , Kanazawa University , Automation Industry Focus , Drug Delivery , Lzheimer 39s Disease ,