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Functional autoantibody in COVID-19 contributes to the 'firestorm' of blood clots and inflammation


Functional autoantibody in COVID-19 contributes to the firestorm of blood clots and inflammation
Researchers at Michigan Medicine have discovered yet another functional autoantibody in COVID-19 patients that contributes to the disease s development and the firestorm of blood clots and inflammation it induces.
A growing body of studies suggests COVID-19 emulates many aspects of systemic autoimmune disorders, including the release of a flurry of overactive immune cells that produce toxic webs of proteins and DNA called neutrophil extracellular traps, or NETs.
For this study, the team analyzed serum from over 300 hospitalized COVID patients, searching for a novel autoantibody that shields the toxic NETs from being destroyed and produces a lasting noxious effect in a patient s body. ....

United States , Yu Ray Zuo , Jason Knight , Yogen Kanthi , Emily Henderson , National Institutes Of Health , National Heart , Blood Institute , Michigan Medicine , Lasker Investigator , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , ஜேசன் நைட் , யோகன் காந்தி , எமிலி ஹென்டர்சன் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , தேசிய இதயம் , இரத்தம் நிறுவனம் , மிச்சிகன் மருந்து , லாஸ்கர் புலனாய்வாளர் , தேசிய நிறுவனங்கள் ,