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Direct Oral Anticoagulant Use for Left Ventricular Thrombus Treatment

An overview of the use of direct oral anticoagulants as an alternative to warfarin in the treatment of left ventricular thrombus.

Albany-medical-center , New-york , United-states , Albany-college-of-pharmacy , American , Cruz-rodriguez , J-cardiovasc-pharmacother , Janssen-carepath , Emilym-persson , Kidoet-al , Katelyn-steverson , Angel-rose-weber

Coronary Artery Bypass Grafting (CABG) | Coronary Artery Bypass Surgery

Coronary artery bypass grafting (CABG) or heart bypass surgery is an open heart surgery to relieve the blockages of the arteries of the heart. Coronary artery bypass surgery lasts up to 3 to 6 hours.

India , United-states , Reneg-favaloro , Rene-favaloro , Robotic-surgery-institute , About-coronary-artery-bypass-grafting , Off-pump-coronary-bypass , Invasive-direct-coronary-artery-bypass , Coronary-artery-disease , Myocardial-infarction , Percutaneous-transluminal-coronary-angioplasty , Coronary-artery-bypass-grafting

Introducing Eternal Coffee Daze: Where Coffee and Fun Collide!

Introducing Eternal Coffee Daze: Where Coffee and Fun Collide!
openpr.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from openpr.com Daily Mail and Mail on Sunday newspapers.

Top-companies , Left-ventricular-dysfunction , Left-ventricular , Quantum-genomics ,

Echocardiography Boosts Prognostic Power in T1D

Myocardial performance index, a heart-function metric derived from echo findings, significantly boosted the ability to predict incident CVD, especially heart failure, in people with type 1 diabetes.

Denmark , Steno , Hovedstaden , Amsterdam , Noord-holland , Netherlands , Copenhagen , Køavn- , Danish , Hashmatsz-bahrami , Copenhagen-university-hospital

Rocket Pharmaceuticals Reaches FDA Alignment on Pivotal Phase 2 Trial Design for RP-A501 in Danon Di

Final alignment reached on a 12 patient, single-arm, open label study with a biomarker based co-primary endpoint assessed at 12 months to support accelerated approvalCo-primary endpoint consisting of LAMP2 protein expression and Left Ventricular (LV) Mass change from baselineCRANBURY, N.J.--(BUSINESS WIRE)--Rocket P...

Kevin-giordano , Gaurav-shah , York-heart-association , Rocket-pharmaceuticals-inc , Drug-administration , Nasdaq , Left-ventricular , Rocket-pharmaceuticals , Danon-disease , Biologics-evaluation , Chief-executive-officer , Kansas-city-cardiomyopathy-questionnaire

World-Renowned Cardiologists and Cardiac Surgeons to Feature Innovative Heart Failure Therapies at Technology and Heart Failure Therapeutics, March 20-22, 2023

/PRNewswire/ -- WHAT: Innovative therapeutic approaches for left ventricular restoration for patients with Heart Failure with Reduced Ejection Fraction (HFrEF)....

Boston , Massachusetts , United-states , Ori-ben-yehuda-bioventrix-inc , Investigational-use , Michael-pfeiffer-penn-state-hershey-medical-center , Bioventrix-inc , Heart-failure , Reduced-ejection-fraction , Left-ventricular , Less-invasive-ventricular-enhancement

'Heart failure is no longer Life failure' as JB Pharma decreases price of critical Heart Failure medicine AZMARDA (Sacubitril-Valsartan) by nearly 50 per cent

Mumbai (Maharashtra) [India], December 5 (ANI/PRNewswire): JB Chemicals & Pharmaceuticals Ltd (JB Pharma), one of the fastest-growing pharmaceutical companies in India, announced a substantial price decrease of approximately 50 per cent for the critical heart failure drug 'Azmarda'. Azmarda, which contains the patented molecule Saccubutril-Valsartan is indicated for Heart failure which ails 8 to 12 million people in the country. After the price reduction, Azmarda (Saccubutril-Valsartan), 50 mg will be available at Rs 39.6 per tablet as compared to Rs 78 per tablet. Commenting on the move, Dilip Singh Rathore, President - Domestic Business, JB Pharma, said, "Being a leading player in the cardiac segment, JB has decided to take the lead in making their Azmarda drug more accessible and affordable for heart failure patients in India. This is in line with our strategy of providing innovative and quality treatment to a larger patient pool at the most affordable price points. With this move, the overall monthly treatment cost will reduce significantly from Rs 4500 to Rs 2200. The HF drug also helps in reducing hospitalization cost by around Rs 1,00,000 at the minimum." He further added, "Heart Failure is a devastating condition and it's important to also increase awareness about the condition. Thus, JB will also institute over 300+ 'Heart failure' clinics across the country so that patients are able to detect the condition early and make informed health decisions." Heart failure is a chronic condition in which the heart doesn't pump blood as well as it should. It is a progressive chronic syndrome characterised by a decrease in functional status and quality of life. Blood often backs up and causes fluid to build up in the lungs (congest) and in the legs. The fluid build-up can cause shortness of breath and swelling of the legs and feet. It is estimated that 8-12 million people in the country suffer from heart failure (HF) as a condition. It often remains undiagnosed, and patients become aware of it mostly at the end-stage. Approximately 80-90 per cent of patients have Left Ventricular HF with a nearly even (50-50) split between HFrEF (Heart Failure Reduced Ejection Fraction) and HFpEF (Heart Failure Preserved Ejection Fraction). Given incidences of hospitalization and high mortality, HF is a specialist-driven condition (50-70 per cent of the patient pool is with Cardiologists and 5-10 per cent with Diabetologists). In India, HF affects a relatively younger population compared to the western world. This move by JB will not only help reduce the cost of treatment but will also help enhance the productive years of patients and their quality of life. HF patients were traditionally prescribed only ARBs (Angiotensin Receptor Blockers) / AI (Ace Inhibitors) as the main medication. Sacubitril+ Valsartan, launched in 2017, is considered superior to ARBs/AIs in raising EF (Ejection Fraction), hence highly effective for HFrEF patients. Sacubitril+ Valsartan is currently prescribed to 30-35 per cent of HFrEF patients while doctors believe the share can go up to 50-65 per cent with the right pricing. As per IQVIA, MAT Sep 22 data Saccubutril- Valsartan is now a Rs 500+ crores market with a 3-year CAGR of ~30 per cent. The molecule is presently patented by Novartis AG, Switzerland and currently, four companies including Novartis are serving the Indian market. The molecule is expected to go off-patent in January 2023. Presently Azmarda is the third largest brand in the category capturing 17 per cent market share with IQVIA MAT OCT'22 sales of Rs 93.5 crores. In April' 22, JB Pharma acquired the Azmarda brand from Novartis AG, Switzerland for the India region for a consideration of Rs 246 crores. JB Pharma, established in 1976, is one of the fastest-growing pharmaceutical companies in India and a leading player in the hypertension segment. Besides its strong India presence, which accounts for majority of its revenue, its other two home markets are Russia and South Africa. In India, the company has five brands among the top 300 IPM brands in the country. The company exports its finished formulations to over 40 countries including the USA. Besides supplying branded generic formulations to several countries, it is also a leader in the manufacturing of medicated lozenges. The company ranks among the top 5 manufacturers globally in medicated and herbal lozenges. It has seven state of the art manufacturing facilities in India including a dedicated manufacturing facility for lozenges. The manufacturing facilities are certified by leading regulators across the world. For more details on JB Pharma, please visit www.jbpharma.com For details of our latest sustainability report, please visit https://jbpharma.com/sustainability-report/ This story is provided by PRNewswire. ANI will not be responsible in any way for the content of this article. (ANI/PRNewswire)

South-africa , United-states , Mumbai , Maharashtra , India , Russia , Switzerland , Dilip-singh-rathore , Azmarda-saccubutril-valsartan , Jb-chemicals-pharmaceuticals-ltd-pharma , Novartis , Pharmaceuticals-ltd

Apple Watch can help detect silent heart disease: Report

The study included 2,454 patients from the US and 11 other countries. From August 2021 to February 2022, these participants sent over 1,25,000 ECGs via their Apple Watch.

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Apple Watch's lifesaving powers could extend to preventing heart failure

A Mayo Clinic study says that Apple Watches could be used to identify Left Ventricular dysfunction of the heart prior to heart failure.

Apple-watch , Left-ventricular , Apple-watches , Nature-medicine , Apple-watch-series , Apple-watch-ultra ,

Veer Sangha Receives AHA Elizabeth Barrett-Connor Research Award

Veer Sangha, an undergraduate researcher at Yale University, received the prestigious Elizabeth Barrett-Connor Research Award for Early Career Investigators.

United-states , American , Rohan-khera , Yale-university , Elizabeth-barrett-connor-research-award , Nature-communications , Cards-lab , Cardiovascular-data-science-cards-lab , American-heart-association-scientific-sessions-on , American-heart-association-council-on-epidemiology , Early-career-investigators , Left-ventricular