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Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer’s disease (AD) therapy. In tests in multiple m
In mice and human cell cultures, MIT researchers showed that lipid nanoparticles can deliver a potential RNA therapy for inflammation in the brain, a prominent symptom in Alzheimer’s disease.
<p>In mice and human cell cultures, MIT researchers showed that novel nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s disease</p>
A new candidate drug reduced inflammation and improved memory in human cell cultures and Alzheimer’s mouse models. The work was co-led by the lab of Li-Huei Tsai at the Picower Institute for Learning and Memory.
A potential new Alzheimer’s drug represses the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons and improving cognition in preclinical tests.