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KU Leuven enters international licence agreement on cancer therapy


KU Leuven enters international licence agreement on cancer therapy
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​​​​​TEAD inhibition holds great promise as a therapeutic approach as the Hippo pathway is genetically altered in up to 10% of cancers.  In mesothelioma, an aggressive and untreatable cancer often caused by asbestos exposure, 60 to 70% of patients have mutations in the Hippo pathway leading to striking sensitivity to TEAD-inhibitors. 
SpringWorks Expects to Nominate a Development Candidate and Commence IND-Enabling Studies in 2022
LEUVEN, Belgium, May 6, 2021 – KU Leuven, CD3 and VIB today announced that they have entered into an exclusive worldwide license agreement with SpringWorks Therapeutics, Inc. (Nasdaq: SWTX) for a portfolio of novel small molecule inhibitors of the Transcriptional Enhanced Associate Domain (TEAD) family of transcription factors, designed for the po ....

Region Flamande , Van Biervliet , Patrick Chaltin , Georg Halder , Springworks Expects To Nominatea Development , Springworks Therapeutics Inc , Centre For Drug Design , Leuven Centre For Cancer Biology , Works Expects , Development Candidate , Enabling Studies , Springworks Therapeutics , Transcriptional Enhanced Associate Domain , Drug Design , Professor Georg Halder , Professor Georg , Managing Director , ஜார்ஜ் ஹால்டர் , மையம் க்கு மருந்து வடிவமைப்பு , வளர்ச்சி வேட்பாளர் , செயல்படுத்துகிறது ஆய்வுகள் , மருந்து வடிவமைப்பு , ப்ரொஃபெஸர் ஜார்ஜ் ஹால்டர் , ப்ரொஃபெஸர் ஜார்ஜ் , நிர்வகித்தல் இயக்குனர் ,