Researchers discover new brain tumor subtypes that could identify treatment for incurable brain cancer miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Research lead by RCSI University of Medicine and Health Sciences has discovered three new subtypes of brain tumor which could help to identify new and effective therapies.
KU Leuven enters international licence agreement on cancer therapy
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TEAD inhibition holds great promise as a therapeutic approach as the Hippo pathway is genetically altered in up to 10% of cancers. In mesothelioma, an aggressive and untreatable cancer often caused by asbestos exposure, 60 to 70% of patients have mutations in the Hippo pathway leading to striking sensitivity to TEAD-inhibitors.
SpringWorks Expects to Nominate a Development Candidate and Commence IND-Enabling Studies in 2022
LEUVEN, Belgium, May 6, 2021 – KU Leuven, CD3 and VIB today announced that they have entered into an exclusive worldwide license agreement with SpringWorks Therapeutics, Inc. (Nasdaq: SWTX) for a portfolio of novel small molecule inhibitors of the Transcriptional Enhanced Associate Domain (TEAD) family of transcription factors, designed for the potential treatme