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FDA Grants Breakthrough Therapy Designation to Inavolisib for PIK3CA-Mutated Breast Cancer

Inavolisib was submitted to the FDA for review as a first-line treatment for advanced HR-positive, HER2-negative PIK3CA-mutated breast cancer. ....

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F. Hoffmann-La Roche Ltd: Roche reports positive Phase I results for its dual GLP-1/GIP receptor agonist CT-388 in people with obesity

F. Hoffmann-La Roche Ltd: Roche reports positive Phase I results for its dual GLP-1/GIP receptor agonist CT-388 in people with obesity
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United States , Yvette Petillon , Simon Goldsborough , Levi Garraway , Kirti Pandey , Sabine Borngr , Rebekka Schnell , Loren Kalm , Birgit Masjost , Nathalie Altermatt , Sileia Urech , Bruno Eschli , Karsten Kleine , Roche Group , Head Of Global Product Development , Chief Medical Officer , Global Product , Dow Jones Sustainability Indices , Chugai Pharmaceutical , Ihr Portfolio ,

[Ad hoc announcement pursuant to Art. 53 LR] Roche reports positive Phase I results for its dual GLP-1/GIP receptor agonist CT-388 in people with obesity

Over 24 weeks, a once-weekly subcutaneous injection of CT-388 achieved a clinically meaningful and statistically significant mean placebo-adjusted weight loss of 18.8% At week 24, 100% of CT-388. ....

United States , Levi Garraway , Simon Goldsborough , Yvette Petillon , Sabine Borngr , Kirti Pandey , Loren Kalm , Rebekka Schnell , Nathalie Altermatt , Sileia Urech , Karsten Kleine , Birgit Masjost , Bruno Eschli , Head Of Global Product Development , Roche Group , Chief Medical Officer , Global Product , Dow Jones Sustainability Indices , Chugai Pharmaceutical ,

Genentech Reports Positive Phase Ib Results for Its Dual GLP-1/GIP Receptor Agonist CT-388 in People With Obesity

Genentech Reports Positive Phase Ib Results for Its Dual GLP-1/GIP Receptor Agonist CT-388 in People With Obesity
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Roche Shares Climb After Weight-Loss Drug Shows Efficacy in Early-Stage Trial

By Adria Calatayud

Roche Holding shares rose after the Swiss pharmaceutical giant said a drug candidate achieved positive results for weight loss in an early-stage clinical trial in adults. ....

Levi Garraway , Eli Lilly , Adria Calatayud , Novo Nordisk , Roche Holding , Carmot Therapeutics , Dow Jones ,