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Myotonic dystrophy type 1 (DM1) is an incurable multisystem disease caused by a CTG-repeat expansion in the DM1 protein kinase (DMPK) gene. The OPTIMISTIC clinical trial demonstrated positive and heterogenous effects of cognitive behavioral therapy (CBT) on the capacity for activity and social participations in DM1 patients. Through a process of reverse engineering, this study aims to identify druggable molecular biomarkers associated with the clinical improvement in the OPTIMISTIC cohort. Based on full blood samples collected during OPTIMISTIC, we performed paired mRNA sequencing for 27 patie...

Global NGS Library Preparation Automation Market to Reach $3,803. 3 Million by 2029. ...

/PRNewswire/ -- BIS Research, the global leader in providing market intelligence on deep technologies, has released its latest study titled NGS Library...

In this article, Roche discusses a novel workflow for NGS library preparation that allows for much more efficient RNA-sequencing.

Investigating the beneficial effects of selenium doped carbon quantum dots supplementation on the in vitro development competence of ovine oocytes. Read more..