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Plasma MTBR-tau243 reflects changes in tau pathology and can be used to stage AD tauopathy and to determine if cognitive symptoms are likely due to AD pathology.

The study is investigating whether high-dose IL-23 inhibition can target resident memory T cells and thereby induce long-term remission.

In a letter, the FDA stated that additional efficacy data are required to support an approval for chronic spontaneous urticaria (CSU), according to the manufacturers of dupilumab.

This result, along with its ease of use, adds to the growing evidence that tenecteplase should be a first-line thrombolytic agent, trial investigators say.

In trauma patients with exsanguinating torso hemorrhage, resuscitative endovascular balloon occlusion of the aorta did not reduce mortality, and may have increased 90-day mortality, in a new trial.