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Ludwig Cancer Research study reveals how certain immune cells in body cavities help suppress anti-tumor immunity - Vimarsana News

Ludwig Cancer Research study reveals how certain immune cells in body cavities help suppress anti-tumor immunity

JUNE 10, 2021, NEW YORK - A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities...

Ludwig Cancer Research study shows how certain macrophages dampen anti-tumor immunity - Vimarsana News

Ludwig Cancer Research study shows how certain macrophages dampen anti-tumor immunity

 E-Mail IMAGE: Ludwig Memorial Sloan Kettering's investigators Taha Merghoub, Jedd Wolchok and assistant attending physician Andrew Chow. view more  Credit: Ludwig Cancer Research JUNE 10, 2021, NEW YORK - A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune system's cancer-killing CD8+ T cells. Reported in the current issue of Cancer Cell and led by Ludwig investigators Taha Merghoub and Jedd Wolchok at Memorial Sloan Kettering (MSK) and C...

Suppressive immune cells' metabolic vulnerability may be targeted for cancer immunotherapy - Vimarsana News

Suppressive immune cells' metabolic vulnerability may be targeted for cancer immunotherapy

 E-Mail IMAGE: Taha Merghoub and Jedd Wolchok of the Ludwig Center at Memorial Sloan Kettering Cancer Center (MSK) and former postdoc Roberta Zappasodi view more  Credit: Ludwig Cancer Research FEBRUARY 15, 2021, NEW YORK - A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors. The tumors in question are relatively less reliant on burning sugar through a biochemical process known as glycolysis. Researchers led by Taha Merghoub and ...