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submitted a bid to buy manchester united — bbc sport understands that a rival bid was also tabled by ineos. now it's time for bittersweet medicine. this is a story of hope. how a new treatment is stopping a devastating genetic disease in its tracks. we have had almost nothing to offer families with this condition for decades. bringing a new medicine to the world that can potentially cure these devastating diseases is incredibly satisfying and rewarding. how britain's most expensive medicine is giving children their lives back. it's amazing. i mean, she's such a little character —...

of genetic conditions. # nala, charlie, nala, charlie shaw... this is the shaw family, from northumberland. mum and dad, ally and jake, and their two daughters, nala and teddi. i've always said nala saved teddi's life. and that's how i've wanted to think about it. whee! the family are living under the shadow of a devastating disease — a rare life—limiting genetic disorder called mld — which is already taking a toll on nala. days out like this are one way the family are building happy memories with their girls. and there's one sure way to please any toddler. more cake? yes, more...

what happened that night? surreal scenes in florida, streets overtaken with water after 2 feet of rain fell in only six hours. the airport shut down. the desperate rescues from homes and cars. how nbc's investigation on migrants working illegally in slaughterhouses revealed a widespread stolen identity scheme the new government warning about a deadly baby sleeper recalled years ago but still turning up for sale online and the inspiring school where everyone learns a language of inclusion. >> announcer: this is "nbc nightly news" with lester holt >> good evening and welcome. t...

the 11th hour with stephanie ruhle starts now >> tonight, donald trump under oath again in new york's lawsuit for alleged business fraud, as the special counse focuses on trump's fundraising in the days after the 2020 election then, the battle over abortion pill access is headed for th supreme court as som republicans struggle to discus the issue. and more questions than answer after today's arrest in th leak of those classified documents on the war in ukraine, as the 11th hour gets underway on this thursday night good evening once again, i'm stephanie ruhle. the recently indicted fo...

otherwise? >> yeah. it's made us a lot closer. every time i signed to him, see a smile on his face. >> after high school, surely i planning on becoming an as interpreter. >> for example, i'm going to the store. >> so, how would you sign that >> i go to store >> and she's already getting started. >> i just feel there should be a lot more - out there for people like my brother. >> it's a sign of what to come rehema ellis, nbc news, ne york >> thank you to the grea rehema ellis and on that note, i wish you a very good night. from all of our colleagues across the network networks of nbc ...