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Credit: Weizhi Ji, Kunming University of Science and Technology
Investigators in China and the United States have injected human stem cells into primate embryos and were able to grow chimeric embryos for a significant period of time up to 20 days. The research, despite its ethical concerns, has the potential to provide new insights into developmental biology and evolution. It also has implications for developing new models of human biology and disease. The work appears April 15 in the journal
Cell.
As we are unable to conduct certain types of experiments in humans, it is essential that we have better models to more accurately study and understand human biology and disease, says senior author Juan Carlos Izpisua Belmonte, a professor in the Gene Expression Laboratory at the Salk Institute for Biological Sciences. An important goal of experimental biology is the development of model systems that allow for the study of human diseases under in vivo conditions. ....

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