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Estimating infectiousness throughout SARS-CoV-2 infection course


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A) Distribution of observed first-positive viral loads for 25,381 subjects according to clinical status (6110 PAMS, 9519 Hospitalised, 9752 Other) and age group. (
B) Age-viral load association with observed viral loads and confidence intervals as circles (with size indicating subject count) with vertical lines, and model-predicted viral loads and credible intervals as a black roughly-horizontal line with grey shading. (
C) Overlapping age histograms according to subject clinical status. Because inclusion in the study required a positive RT-PCR test result, and testing is in many cases symptom-dependent, the study may have a proportion of PAMS cases that differs from the proportion in the general population. ....

Eteläuomen Läi , Hong Kong , United Kingdom , Leonie Meiners , Manuel Holtgrewe , Stephen Kissler , Oliver Stolpe , Udo Gieraths , Dieter Beule , German Federal Ministry Of Education , Institute Of Virology , European Commission , Berlin Institute Of Health , Research Clinic , Berlin Institute Of Virology , Institute Of Virology At Charit , German Ministry Of Health Konsiliarlabor , Research Bundesministerium , Berlin Institute , Labor Berlin , Among Hospitalised , Roche Light Cycler , Geneious Prime , Potential Scale Reduction Factors , Digital Supplement , Thermofisher Scientific ,