Not just a phase for RNAS
E-Mail IMAGE: Image shows cells with oil droplet-like 'NORAD-Pumilio bodies' in red and nucleus in blue. Credit: Mahmoud Elguindy view more Credit: Mahmoud Elguindy DALLAS - June 9, 2021 - A phenomenon in which an RNA named NORAD drives a protein named Pumilio to form liquid droplets in cells, much like oil in water, appears to tightly regulate the activity of Pumilio. A new study led by UT Southwestern scientists suggests that such RNA-driven "phase separation," in turn, protects against genome instability, premature aging, and neurodegenerative diseases, and may represent a prev...
Source: eurekalert.org