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CCS-enabled 4D proteomics offers major enhancements for timsTOF Pro 2, timsTOF fleX and timsTOF SCP mass spectrometers

CCS-enabled 4D proteomics offers major enhancements for timsTOF Pro 2, timsTOF fleX and timsTOF SCP mass spectrometers

Apr 22 2021 Read 4 Times A new mass spectrometric acquisition technology, Scanning SWATH, which measures the human proteome substantially faster and at a lower cost than its predecessors, has been developed by researchers at the Francis Crick Institute. The scientists, who have used the new approach to uncover key proteins in the body’s response to COVID-19, hope it will lead to more effective drug screening and biomarker discovery. Measuring the activity of different proteins in our bodies requires analysis of cells, tissues or blood samples usually obtained with mass spectrometry; however...

Researchers examine proteins involved in SARS-CoV-2 infection Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate. Scientists from Charité - Universitätsmedizin Berlin and from the Berlin Institute of Health (BIH), along with colleagues from the United Kingdom, Germany and the United States, have examined the corresponding genes of the helper proteins in a large study. They discovered numerous variants that influence the amount or functi...

 E-Mail IMAGE: Red: proteins required by the virus, blue: proteins associated with severe COVID-19 disease; the higher the peak, the higher the probability that there is actually a connection. view more  Credit: Image: M. Pietzner Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate. Scientists from Charité - Universitätsmedizin Berlin and from the Berlin Institute of Health (BIH), along with colleagues from the United Kingdom, ...