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Researchers investigated the extent of nosocomial SARS-CoV-2 infection among elderly patients and healthcare workers in a geriatric hospital.

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for DENV infection using IgM, IgG and qPCR assay; where 76 samples were positive for DENV and analysed ...

Phylogenetic analyses shows SARS-CoV-2 variant B.1.1.7 originated in the UK The emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has marked a new phase in the COVID-19 pandemic. Phylogenetic and epidemiological investigations suggest that the SARS-CoV-2 genetic lineage B.1.1.7 may be associated with increased viral transmissibility among humans. It was also classified as a "Variant of Concern" (VOC B.1.1.7) in December 2020. First discovered in Kent, United Kingdom, in September 2020, this new variant has since been found in more than 29 countries across ...

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences In a recent bioRxiv* preprint study, researchers from the University of Hawaii showed that the S gene of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously mutating according to the sequence and phylogenetic analysis. At the same time, a unique strain with an emerging mutation in an altered spike glycoprotein may be present in Hawaii. Over the past year, there was a notable evolution of SARS-CoV-2 around the globe, which will continue to pose a serious threat. As of January 2021...