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Dyne Therapeutics Announces New Clinical Data from ACHIEVE Trial of DYNE-101 in DM1 and DELIVER Trial of DYNE-251 in DMD Demonstrating Compelling Impact on Key Disease Biomarkers and Improvement in Multiple Functional Endpoints

- In Phase 1/2 ACHIEVE Trial, DYNE-101 Demonstrated Dose Dependent 27% Mean Splicing Correction Across All Patients in the 5.4 mg/kg Cohort at 3 Months - - DYNE-101 Showed Improvement in Myotonia,. ....

United States , Stacy Nartker , Wildon Farwell , Amy Reilly , John Cox , Exchange Commission , Drug Administration , Myotonic Dystrophy Health Index , European Medicines Agency , Dyne Therapeutics Inc , Dose Dependent , Mean Splicing Correction Across All Patients , Muscle Strength , Timed Function Tests , Reported Outcomes , Mean Unadjusted , Mean Muscle Adjusted , Dystrophin Expression , Cohort Administered Monthly , Higher Level , Dystrophin Than Reported , Weekly Administered Standard , Functional Improvement , Run Time , Stride Velocity , Safety Profiles ,

Dyne Therapeutics Announces New Clinical Data from ACHIEVE

- In Phase 1/2 ACHIEVE Trial, DYNE-101 Demonstrated Dose Dependent 27% Mean Splicing Correction Across All Patients in the 5.4 mg/kg Cohort at 3 Months - . ....

United States , Amy Reilly , John Cox , Stacy Nartker , Wildon Farwell , Exchange Commission , Dyne Therapeutics Inc , European Medicines Agency , Drug Administration , Myotonic Dystrophy Health Index , Dose Dependent , Mean Splicing Correction Across All Patients , Muscle Strength , Timed Function Tests , Reported Outcomes , Mean Unadjusted , Mean Muscle Adjusted , Dystrophin Expression , Cohort Administered Monthly , Higher Level , Dystrophin Than Reported , Weekly Administered Standard , Functional Improvement , Run Time , Stride Velocity , Safety Profiles ,