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A systematic review and meta-analysis support the use of oral naltrexone and acamprosate, coupled with psychosocial support, to reduce drinking among adults with alcohol use disorder.
Investigators say their meta-analysis of 16 trials spanning six decades highlights the benefits patients and oncologists can expect from regional lymph node radiation for early breast cancer.
Further analyses from the ARTESIA study and the previous NOAH-AFNET 6 trial are needed to try to identify groups where the benefit may outweigh the risk, researchers say.
Patients with immune-mediated diseases and a history of malignancy had similar rates of cancer recurrence whether or not they were receiving immunosuppressive treatments.
'Given the increased risk of postcolonoscopy colorectal cancer associated with low ADR, improving [this performance metric] has become a major focus for quality improvement.'