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Novel approach to interrogate tissue-specific protein-protein interactions

Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing. ....

Xiang David Li , Li Ka Shing , Xiang David , Chaogu Zheng , School Of Biomedical Sciences , Proceedings Of The National Academy Sciences , Department Of Chemistry , School Of Biological Sciences , University Of Hong Kong , Hong Kong , Professor Xiang David , Professor Chaogu , Biological Sciences , Biomedical Sciences , Methionine Analog Based Cell Specific Proteomics , National Academy ,

Novel Method to Understand Organ Development, Disease Pathogenesis Unveiled

Novel Method to Understand Organ Development, Disease Pathogenesis Unveiled
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Ka Shing , Hong Kong , University Of Hong Kong , Hong Kong General , Xiang David , Li Ka Shing , Chaogu Zheng , Xiucong Bao , Xiang David Li , Siyue Huang , School Of Biomedical Sciences , National Natural Science Foundation Of China , Health Bureau , Research Fund , School Of Biological Sciences , Strategic Interdisciplinary Research Scheme , Department Of Chemistry , School Of Biological Sciences Faculty Science , Proceedings Of The National Academy Sciences , Department Of Chemistry Faculty Science , Professor Xiang David , Professor Chaogu , Biological Sciences , Biomedical Sciences , Methionine Analog Based Cell Specific Proteomics , National Academy ,

Scientists develop novel approach to interrogate tissue-specific protein–protein interactions

Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. ....

Xiang David Li , Chaogu Zheng , Siyue Huang , Xiucong Bao , Li Ka Shing , Department Of Chemistry , Proceedings Of The National Academy Sciences , School Of Biological Sciences , University Of Hong Kong , School Of Biomedical Sciences , National Academy , Hong Kong , Professor Chaogu Zheng , Biological Sciences , Biomedical Sciences , Methionine Analog Based Cell Specific Proteomics , Professor Xiang David , Professor Chaogu ,