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Monkey study points to HIV vulnerability for vaccine attack

Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people. ....

National Institute Of Allergy , Vaccine Research Center , National Institutes Of Health , Nih National Institute Of Allergy , National Institute , Science Translational Medicine , Infectious Diseases , National Institutes , Cell Culture , Hiv 1 , Infectious Diseases , Medical Research ,

NIAID study identifies critical t-cell function missing in prior HIV vaccine candidates

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues. ....

Laboratory Of Immunoregulation , Nih National Institute Of Allergy , National Institute Of Allergy , National Institutes Of Health , National Institute , Infectious Diseases , National Institutes , Specific Immunity Section , Immune Response , Immune System , Infectious Diseases , Medical Research , T Cell ,

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

New research helps explain why young children have lower rates of severe COVID-19 than adults. A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood. ....

Stanford University , United States , Mary Allen Staat , Bali Pulendran , Danielle Ellis , Violettal Horton , National Institute Of Allergy , National Institutes Of Health , Institute For Immunology , National Institute , Infectious Diseases , National Institutes , Cincinnati Children , Kulkarni Endowed Chair , Ars Cov 2 , Covid 19 , Immune Response , Infectious Diseases , Medical Research ,