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Zanidatamab exhibits 'promising' efficacy in advanced HER2-positive biliary tract cancer

CHICAGO — Zanidatamab exhibited durable antitumor activity among patients with previously treated advanced HER2-amplified biliary tract cancer, according to results of the phase 2B HERIZON-BTC-01 study presented at ASCO Annual Meeting.More than half of patients who received zanidatamb (Jazz Pharmaceuticals/Zymeworks) monotherapy survived at least a year and median OS exceeded 15 months. ....

United States , Bymark Leiser , Mindy Valcarcel , University Of Texas Md Anderson Cancer Center , Jazz Pharmaceuticals Zymeworks , Jazz Pharmaceuticals , Shubham Pant , Cancer Center ,

Trastuzumab deruxtecan improves PFS in pretreated breast cancer

CHICAGO — Trastuzumab deruxtecan extended PFS compared with standard chemotherapy for certain patients with pretreated breast cancer, according to findings presented at ASCO Annual Meeting.The analysis — which included patients with hormone receptor-positive, HER2-low or HER2-ultralow metastatic breast cancer that progressed after endocrine therapy — also showed considerably ....

United States , Giuseppe Curigliano , Mindy Valcarcel , Daiichi Sankyo , Bymark Leiser , University Of Milan , European Institute Of Oncology , European Institute ,

High-deductible health plans linked to shorter survival for cancer survivors

CHICAGO — High-deductible health plans appeared associated with shorter survival among cancer survivors, according to results of a nationwide population-based analysis presented at ASCO Annual Meeting.The findings suggest high-deductible health plans may create a financial disincentive for cancer survivors that prevents them from seeking necessary medical care, according to Justin Barnes, ....

United States , Justin Barnes , Mindy Valcarcel , Bymark Leiser , National Death Index , American Cancer Society , Washington University School Of Medicine , National Health Interview , Washington University School , Health Interview Survey ,

Geriatric oncology award recipient aims to 'right-size' cancer treatment for older adults

William Dale, MD, PhD, FASCO, has experienced a range of emotions since learning he’d receive the B.J. Kennedy Geriatric Oncology Award at this year’s ASCO Annual Meeting.The sense of honor he feels for recognition of his contributions to the field is accompanied by a deep gratitude for two past recipients — the late Arti Hurria, MD, FASCO, who received the award in 2013, ....

United States , Mindy Valcarcel , Heidi Diana Klepin , Byjennifer Byrne , Heidi Klepin , William Dale , Wake Forest University School Of Medicine , Research Group , City Of Hope Department , Geriatric Oncology Award , Arti Hurria , George Tsai Family Chair , Geriatric Oncology , Aging Research Group , Wake Forest University School , North America ,

Findings highlight need to improve prior authorization process for cancer pain management

CHICAGO — A review of more than 1,700 prior authorization requests related to pain medication for people with cancer showed the vast majority ultimately got approved.However, chart reviews documented uncontrolled pain and unmanageable side effects for many patients whose requests had been denied. ....

United States , Fumiko Chino , Mindy Valcarcel , Bymark Leiser , Memorial Sloan Kettering Cancer Center , Healio Women , Oncology Peer Perspective Board , Capitol Hill ,