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(doi:10.1001/jamainternmed.2021.2209) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. ### Media advisory: The full study is linked to this news release. Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https:/

For many diseases, overweight and obesity are risk factors. But now a study shows that a higher BMI may be linked to higher survival rates in patients hospitalized for severe bacterial infections.

 E-Mail COLUMBUS, Ohio - Though obesity in midlife is linked to an increased risk for Alzheimer's disease, new research suggests that a high body mass index later in life doesn't necessarily translate to greater chances of developing the brain disease. In the study, researchers compared data from two groups of people who had been diagnosed with mild cognitive impairment - half whose disease progressed to Alzheimer's in 24 months and half whose condition did not worsen. The researchers zeroed in on two risk factors: body mass index (BMI) and a cluster of genetic variants associated with highe...

(doi:10.1001/jamacardio.2021.0487) Editor's Note: The article includes conflict of interest disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support. #  #  # Media advisory: The full study and commentary are linked to this news release. ### Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system. Share

Credit: Newcastle University, UK New research has shown that people with type 1 diabetes may have features of premature heart disease induced by the condition often before they even get their diagnosis. Early markers for this heart disease could be used to ensure patients get targeted therapies as soon as they are diagnosed with type 1 diabetes to slow down or even halt cardiovascular problems. The findings, published in Stem Cell Research and Therapy, show that tiny pieces of genetic material, called miR-424-5p, increased in early stages of heart disease - these could be targeted to help re...