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Women taking birth control pills with estrogen more likely to have adverse events, study finds

Though the absolute risk is low, clinicians can advise their female patients on ways to avoid what might be additive risks.

Women who use non-steroidal anti-inflammatory painkillers alongside hormonal contraception appear to be at a small increased risk of blood clots known as venous thromboembolism (VTE), finds a large Danish study published by The BMJ today

Research suggests that women should consider alternatives to avoid 'potentially fatal event'

A harmful drug interaction that deserves more attention Venous thromboembolism is a multifactorial disease, involving interactions between inherited and acquired risk factors such as immobilisation, active cancer, trauma or fracture, recent surgery, and—in young women—pregnancy and hormonal contraception.1 The magnitude of the risk from combined hormonal contraception depends on the dose of oestrogen and type of progestin.2 Although oestrogen causes hypercoagulability by promoting gene transcription of multiple coagulation factors, the role of progestin is less clear.3 In a linked paper, M...