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Jennifer O'Dell, 72, told an inquiry into the scandal that she suffered night terrors and high blood pressure and had to withdraw her to become an MP after she was suspended in 2010.
Wendy Martin opened her own Post Office in York in February 2015 and told the hearing she immediately faced problems with the computer systems.
The chair of the public inquiry into the Post Office Horizon scandal has raised questions over the fairness of the current compensation scheme for victims.
Wendy Martin suffered sleepless nights, constant kidney infections and a suspected stroke after opening her own Post Office in York in February 2015.
The threat of a court trial hung over Susan Hazzleton, 68, who ran a Post Office branch in Little Waltham, Essex, for 18 months after shortfalls started appearing in 2000.