Oxford 12-year-old joins research programme for rare disease
A girl from Oxford who is suffering from a rare autoinflammatory disease has joined a national programme aiming to further studies into similar…
Source: oxfordmail.co.uk
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Secarna Pharmaceuticals publishes new preclinical data in The Journal of Immunology demonstrating potent therapeutic activity of LNAplus™ ASO targeting NLRP3 in highly debilitating autoinflammatory diseases
<ul> <li> Secarna's LNAplus™ ASOs suppress expression of NLRP3, a central component of the inflammasome pathway, which is overactive in many inflammatory diseases </li> <li> Cryopyrin-associated periodic syndrome (CAPS) is a group of rare inherited autoinflammatory diseases driven by overactive NLRP3, resulting in systemic inflammation </li> <li> With NLRP3-specific ASOs, inflammatory downstream effects were interrupted in immune cells and strong symptom relief and significant prolongation of survival was achieved in a CAPS disease mo...
Source: whatech.com
Secarna Pharmaceuticals publishes new preclinical data in The Journal of Immunology demonstrating potent therapeutic activity of LNAplus™ ASO targeting NLRP3 in highly debilitating autoinflammatory diseases
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Source: livenews.co.nz
The first case of NLRP3-AID in Ecuador
A 9-year-old patient with recurrent fever, urticarial rash and demyelinating brain lesions: nlrp3- autoinflammatory disease in Ecuador
Source: dovepress.com