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Gefitinib with Chemotherapy in EGFR-Mutated Lung Cancer

1. The median overall survival was 17.6 months in the gefitinib group vs 27.5 months in the gefitinib plus chemotherapy group, with HR 0.58 (significant). 2. The 5-year progression-free survival was 1.71% in the gefitinib group vs 6.67% in the gefitinib plus chemotherapy group, with HR 0.53 (significant). Evidence Rating Level: 1 (Excellent) Study Rundown: ....

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FDA Approves Osimertinib With Chemotherapy for EGFRm NSCLC

Osimertinib was previously approved as a monotherapy, the first-in-line global standard of care, for non–small cell lung cancer indications. ....

Davida Litman , Dave Fredrickson , Dana Farber Cancer Institute , Osimertinib With , Line Treatment , Completion Date , Oncology Business Unit , Thenew England Journal , Yang Jc H , Mutated Advanced ,