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without it. >> rachel, i think my patients are because when your appetite is zoned down and insulin is working better these discussion, especially mounjaro effects two appetite receptors in the brain and stomach. you rye really start craving after a while healthier foods. it's also anti-aging treatment, rachel, believe it or not, because it when you are stabilizing insulin, which is a hormone that doesn't work as well as we get older, you know, not only are you able to burn fat, which is what insulin does, cure exercise more efficiently, you are also building bone and muscle. and whe...

the supreme court for more than two decades and was at the center of some of the most impactful decisions impacting the lives of all americans. >> thank you for joining us. the lead with jake tapper starts right now. >> team trump just took out its first new hampshire ad against nikki haley. the lead starts now. by this time, next month, we will know if the polls are right. >> do you hear that sound? that's the sound of us surging. >> this hour i will speak with haley's biggest supporter in new hampshire where she has got to stop trump if she wants to be president, plus democratic se...

drugs. tough, new auto emission standards about to be announced, but will they push more americans to go electric a big upside of artificial intelligence, detecting cancer much earlier, and predicting when it might strike and the young, bold athletes sharing their culture and superstar tony hawk. >> announcer: this is "nbc nightly news" with lester holt >> welcome. once again, in the tragic aftermath of a mass shooting, we're getting a person look at pol risking their own lives to stop an active shooter late this afternoon, louisville police releasing body cam video of officers...

tightest match ups. >> fetterman, he keeps getting it wrong that extreme radical ideas. >> if you have never had experience of living in pennsylvania how can you effectively fight for pennsylvania? >> ask or send a panel whether either side can move the needle this late in the game. >> the fight lived in pennsylvania i would already cast my vote for john fetterman for many reasons. six then a warning from our house and democrat on the states on tuesday. >> losing this democracy could very well be the end of the war progressed congressman jim clyburn joins us on the stark comments and...

$4000 a year in income since the president took office. lucas tomlinson's life for us in wilmington, delaware with the very latest, lucas. >> good afternoon aishah. the dow is down below when present biden took office inflation is up 40 years i the s&p 500 is down 17% this year for president biden's top economic advisor acknowledging the squeeze many americans are feeling. >> food prices are to hyperinflation is still too h high. the president understands that because his whole focus is defending working families. he knows even with the stronger job market, lower unemployment, he kno...