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World's first fully reversible manipulation of the circadian clock


World s first fully reversible manipulation of the circadian clock
The Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) research team of Designated Associate Professor Tsuyoshi Hirota, Postdoctoral Fellow Simon Miller, Professor Kenichiro Itami and graduate student Tsuyoshi Oshima (Research Fellowship for Young Scientists, JSPS), in collaboration with the group of Professor Ben Feringa and Postdoctoral Fellow Dušan Kolarski of Groningen University in the Netherlands, have achieved a world first: fully reversible manipulation of the period of the circadian clock using light, by exchanging part of a compound with a light-activated switch.
Waking in the morning, sleeping at night - the majority of our biological activities repeat within a daily cycle. The internal process which governs this rhythm is known as the circadian clock. While it is understood that the circadian clock is controlled by the combined functions of clock genes and clock proteins, th ....

Tsuyoshi Hirota , Kenichiro Itami , Simon Miller , Ben Feringa , Emily Henderson , Tsuyoshi Oshima Research Fellowship For Young Scientists , Nagoya University Institute Of Transformative Bio , Groningen University , Nagoya University Institute , Transformative Bio Molecules , Designated Associate Professor Tsuyoshi Hirota , Postdoctoral Fellow Simon Miller , Professor Kenichiro Itami , Tsuyoshi Oshima , Research Fellowship , Young Scientists , Professor Ben Feringa , Circadian Rhythm , சிமோன் மில்லர் , எமிலி ஹென்டர்சன் , நாகோயா பல்கலைக்கழகம் நிறுவனம் ஆஃப் உருமாறும் உயிர் , க்ராநிகந் பல்கலைக்கழகம் , நாகோயா பல்கலைக்கழகம் நிறுவனம் , உருமாறும் உயிர் மூலக்கூறுகள் , போஸ்ட்‌டாக்டொரல் சக சிமோன் மில்லர் , ஆராய்ச்சி கூட்டுறவு ,