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Researchers use X-rays to find the best antibodies

Researchers use X-rays to find the best antibodies
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Andrew Kruse , Craig Ogata , Edwardp Harvey , Nature Communications , Office Of Science , National Cancer Institute Structural Biology Facility , Molecular Pharmacology At Harvard Medical School , Argonne National Laboratory , Us Department Of Energy , National Institute , Argonnex Rays , Biological Chemistry , Molecular Pharmacology , Harvard Medical , Advanced Photon Source , General Medical Sciences ,

Researchers reveal a promising target for designing anti-cancer therapies

Researchers reveal a promising target for designing anti-cancer therapies
Chances are, every one of us has been affected by cancer in one way or another. Unlike some other deadly diseases, cancer can take many forms inside the human body, so learning more about a single enzyme linked to many types of this disease could lead to more effective treatments.
Researchers using the powerful X-ray beams generated at the Advanced Photon Source (APS), a U.S. Department of Energy (DOE) Office of Science User Facility at DOE s Argonne National Laboratory, have determined the structure of just such an enzyme: Taspase1, which plays an integral role in the production of cancer cells in humans. ....

United States , Petra Fromme , Robert Fischetti , Josem Martin Garcia , Michael Becker , Emily Henderson , X Ray Sciences Division At Argonne , Arizona State University , Rocasolano Institute Of Physical Chemistry , National Institutes Of Health , National Cancer Institute Structural Biology Facility , Us Department Of Energy , Office Of Science User Facility , Argonne National Laboratory , National Institute , Advanced Photon Source , Science User Facility , National Laboratory , Rocasolano Institute , General Medical Sciences , Physical Chemistry , Arizona State , X Ray Sciences Division , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , பெட்ரா என்னிடமிருந்து ,

Tiny antibodies naturally generated by llamas can be effective against COVID-19

Tiny antibodies naturally generated by llamas can be effective against COVID-19
As the fight against COVID-19 continues, scientists have turned to an unlikely source for a potentially effective treatment: tiny antibodies naturally generated by llamas.
While the world has welcomed the news of multiple vaccines against COVID-19, the search for effective treatments for those who contract the virus is ongoing. Now scientists are looking to what might seem to be an unlikely source: the South American llama.
Researchers are using the ultrabright X-rays of the Advanced Photon Source (APS), a U.S. Department of Energy (DOE) Office of Science User Facility at DOE s Argonne National Laboratory, to help turn naturally generated llama antibodies into potentially effective therapies against SARS-CoV-2, the virus that causes COVID-19. Antibodies are the immune system s natural defense against infection, and when extracted from blood, they can be used to design treatments and vaccine ....

United States , Nordrhein Westfalen , University Of Texas , Yufei Xiang , Jason Mclellan , Emily Henderson , Xavier Saelen , Yi Shi , Ian Wilson , Cheng Zhang , Andrzej Joachimiak , Daniel Wrapp , Scripps Research Institute , National Institutes Of Health , National Institute Of Arthritis , National Cancer Institute Structural Biology Facility , Us Department Of Energy , Office Of Science User Facility , University Of Texas At Austin , University Of Bonn , University Of Pittsburgh , Argonne National Laboratory , Structural Biology Center , National Institute , South American , Advanced Photon Source ,

Why the lovable llama might be a secret weapon against COVID-19

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As the fight against COVID-19 continues, scientists have turned to an unlikely source for a potentially effective treatment: tiny antibodies naturally generated by llamas.
While the world has welcomed the news of multiple vaccines against COVID-19, the search for effective treatments for those who contract the virus is ongoing. Now scientists are looking to what might seem to be an unlikely source: the South American llama.
Researchers are using the ultrabright X-rays of the Advanced Photon Source (APS), a U.S. Department of Energy (DOE) Office of Science User Facility at DOE s Argonne National Laboratory, to help turn naturally generated llama antibodies into potentially effective therapies against SARS-CoV-2, the virus that causes COVID-19. Antibodies are the immune system s natural defense against infection, and when extracted from blood, they can be used to design treatments and vaccines. ....

United States , Nordrhein Westfalen , Yufei Xiang , Jason Mclellan , Xavier Saelen , Yi Shi , Ian Wilson , Cheng Zhang , Andrzej Joachimiak , Daniel Wrapp , National Institute Of Arthritis , National Cancer Institute Structural Biology Facility , Us Department Of Energy , Environmental Research , Office Of Science , University Of Pittsburgh , Argonne National Laboratory , National Virtual Biotechnology Laboratory , Structural Biology Center , National Institute , Scripps Research Institute , National Institutes Of Health , Office Of Science User Facility , University Of Texas At Austin , University Of Bonn , Argonne National Laboratory Under Contract No ,