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Corbus rockets on early clinical data for next-gen Nectin-4 ADC candidate - Vimarsana News

Corbus rockets on early clinical data for next-gen Nectin-4 ADC candidate

Shares of Corbus Pharmaceuticals Inc. (NASDAQ:CRBP) doubled on opening Jan. 26 and ended the day up a whopping 249% as investors got a look at data from a first-in-human study testing next-generation Nectin-4-targeted antibody-drug conjugate (ADC) CRB-701. Licensed from CSPC Pharmaceutical Group for $7.5 million up front in February 2023, CRB-701 has IND clearance from the U.S. FDA, and Corbus plans to start its own clinical testing in the first quarter of 2024.

NECTIN-4 Offers Attractive Target in Urothelial Cancer and Beyond - Vimarsana News

NECTIN-4 Offers Attractive Target in Urothelial Cancer and Beyond

As the treatment paradigm in urothelial cancer expands to include agents directed at various targets, NECTIN-4 has emerged as a promising treatment target.