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Spinal cord treatment offers relief and sensation to lower limb amputees

Researchers from the USA used commercially available electrodes for closed-loop spinal cord stimulation in three individuals with transtibial amputation. ....

United States , Nature Biomedical Engineering , Diabetic Peripheral Neuropathy , Peripheral Neuropathy , Phantom Limb , Spinal Cord Stimulation ,

Vertex Spikes On Positive Phase 2 Trial Results For VX-548 In Painful Diabetic Neuropathy

Shares of Vertex Pharmaceuticals Inc. (VRTX) are progressing more than 9 percent on Wednesday morning trade after reporting positive results for its phase 2 study of VX-548 for the painful diabetic peripheral neuropathy. ....

Vertex Pharmaceuticals Inc , Vertex Pharmaceuticals , Vertex Pharma , Stock Alert , Vx 548 ,

Dr. William Porter McRoberts rejoins Holy Cross Medical Group from private practice

Interventional spine and pain specialist William Porter McRoberts, MD, returns to Holy Cross Medical Group in Ft. Lauderdale, FL. He has performed over 55,000 s ....

United States , William Porter Mcroberts , Holy Cross Health , Holy Cross Medical Group , South Florida Hospital , Holy Cross , Interventional Spine , Acroiliac Pain , Hronic Post Surgical Pain , Degenerative Disc Disease , Joint Pain , Facial Pain , Pelvic Pain , Spinal Fracture ,

A Role for Neurologists in Diabetic Peripheral Neuropathy

The rise in diabetic neuropathy over the last few decades has paralleled the obesity and related diabetes pandemics, one expert says, and neurologists have a role to play in controlling it. ....

Ann Arbor , United States , Eval Feldman , World Congress , Huge Public Health Problem , University Of Michigan , Medscape Medical , Diabetic Neuropathy , Diabetic Neuropathies , Iabetic Nerve Damage , Peripheral Neuropathy Diabetic , Iabetes Peripheral Neuropathy , Peripheral Neuropathy , Weight Management , Weight Gain , Diabetes Mellitus Type 2 , Iabetes Mellitus Type Ii , Type 2 Diabetes , Pain Management , Pain Management , Body Mass Index Bmi , Diabetic Foot Ulcers ,

"Impact of SGLT2 Inhibitors on Corneal Nerve Morphology and Dendritic C" by Kofi Asiedu, Shyam Sunder Tummanapalli et al.

Purpose: This study aims to determine the effects of SGLT2 inhibitors on corneal dendritic cell density and corneal nerve measures in type 2 diabetes. Methods: Corneal dendritic cell densities and nerve parameters were measured in people with type 2 diabetes treated with SGLT2 inhibitors (T2DM-SGLT2i) [n = 23] and those not treated with SGLT2 inhibitors (T2DM-no SGLT2i) [n = 23], along with 24 age and sex-matched healthy controls. Results: There was a reduction in all corneal nerve parameters in type 2 diabetes groups compared to healthy controls (All parameters: p < 0.05). No significant differences in corneal nerve parameters were observed between T2DM-SGLT2i and T2DM-no SGLT2i groups (All parameters: p > 0.05). Central corneal dendritic cells were significantly reduced [mature (p = 0.03), immature (p = 0.06) and total (p = 0.002)] in the T2DM-SGLT2i group compared to the T2DM-no SGLT2i group. Significantly, higher mature (p = 0.04), immature (p = 0.004), total (p = 0.002) dend ....

Corneal Nerves , Dendritic Cells , Sglt2 Inhibitor ,