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Coincidence or caused by vaccine? OB/GYN addresses concerns about vaccineâs effect on womanâs menstrual cycle Can the COVID-19 vaccine affect your menstrual cycle? By Kristi O Connor | April 29, 2021 at 5:27 PM EDT - Updated April 29 at 6:35 PM CHARLOTTE, N.C. (WBTV) - About 55 percent of the people vaccinated in north Carolina are women. In South Carolina, about 57 percent of the people vaccinated are women. But health officials know there are still some women who are hesitant to get the vaccine because of concerns that it will affect their chance at having a family. Recently, there have been several anecdotal reports of women who say they noticed changes in their menstrual cycles after getting the COVID-19 vaccine. ....