Dr Punekar on the Importance of Complete Biomarker Testing in Lung Cancer
Salman R. Punekar, MD, discusses the importance of complete biomarker testing and the landscape of biomarkers in lung cancer.
Source: onclive.com
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Lung Cancer Radiation May Up AF Risk
During radiotherapy for non–small cell lung cancer, an incidental dose of radiation to the pulmonary veins may trigger atrial fibrillation, a study has found.
Source: medscape.com
Merck Says Keytruda Combination Gets Positive EU CHMP Opinion As Neoadjuvant Treatment For NSCLC
Drug major Merck & Co., Inc. (MRK) announced Friday that the European Medicines Agency's Committee for Medicinal Products for Human Use or CHMP adopted a positive opinion recommending approval of its anti-PD-1 therapy KEYTRUDA, in combination with platinum-containing chemotherapy.
Source: rttnews.com
Perioperative Pembrolizumab Regimen Receives Positive CHMP Opinion in NSCLC
Pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab has been recommended for approval in high-risk NSCLC by the EMA's CHMP.
Source: onclive.com
ASCT2 inhibitors show utility in resistant NSCLC models
Alanine-serine-cysteine transporter 2 (ASCT2) is a glutamine (Gln) transporter that is required for cell proliferation and is overexpressed in tumors such as non-small-cell lung cancer (NSCLC). Researchers from China Pharmaceutical University have reported on the discovery and preclinical characterization of a novel series of ASCT2 inhibitors that led to the identification two lead compounds.
Source: bioworld.com