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Survivors of childhood cancer are at excess risk of late mortality even 40 years from diagnosis, due to many of the leading causes of death in the US population. Modifiable lifestyle and cardiovascular risk factors associated with reduced risk for late mortality should be part of future interventions.

The goal of obesity management is to improve health. Sustained weight loss of more than 10% overall bodyweight improves many of the complications associated with obesity (eg, prevention and control of type 2 diabetes, hypertension, fatty liver disease, and obstructive sleep apnoea), as well as quality of life. Maintenance of weight loss is the major challenge of obesity management. Like all chronic diseases, managing obesity requires a long-term, multimodal approach, taking into account each individual's treatment goals, and the benefit and risk of different therapies.

The present study evaluated the efficacy of polysaccharides as prebiotics for the skin microbiome. Hyaluronic acids, carboxymethyl beta-glucan, glucomannan and schizophyllan were tested and changes in Staphylococcus epidermidis and Cutibacterium acnes were measured in vitro and in vivo.