PFO Closure for Migraine: Pooled Analysis Hints at Benefit Over Meds Alone
February 09, 2021 Patent foramen ovale (PFO) closure in conjunction with optimal medical therapy can reduce both the number of migraine days and the frequency of attacks compared with medicine alone, according to a new pooled analysis. The findings are unlikely to have an effect on clinical practice, as regulatory bodies have not approved any PFO closure device for the treatment of migraine. However, the procedure is now an option for the prevention of PFO-associated stroke. “What this [study] will do is increase people's interest and whet their appetite for the next clinical trial, but it...