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Higher cardiorespiratory fitness may be protective against breast cancer in postmenopausal women

1. In this prospective cohort study, higher cardiorespiratory fitness (CRF) was associated with a substantially lower risk of breast cancer in postmenopausal women. 2. However, this protective effect of high CRF was only seen in those with overweight/obesity or a higher body fat percentage. Evidence Rating Level: 2 (Good) Several risk factors exist for developing ....

Rating Level , United Kingdom Biobank , Body Fat Percentage , Breast Cancer , Cardiorespiratory Fitness ,

Clinical Case 2: High-Risk Early-Stage HR+ Breast Cancer

Rachel Layman, MD, presents a clinical case of a patient who is diagnosed with HR+ early-stage breast cancer. ....

Breast Cancer , Clinical Case , High Risk , In Situ Carcinoma ,

Cell Protein GRP78 Affects Cancer Cell Spread, USC Study Reveals

New research suggests that when cancer cells are under stress, cellular chaperone protein GRP78 alters its behavior and migrates to the cell's nucleus, where it modifies gene activities and allows cancer cells to become more mobile and invasive. ....

Proceedings Of The National Academy Sciences , National Academy , Keck School , Southern California , Cancer Cell , Chaperone Protein , Keck School Of Medicine ,