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| 2 Minute Medicine

1.The objective response rate was 30.8% with the majority attributing to partial response. 2. Most common adverse events (grade 3 or higher) included anemia, fatigue, and hypertension, with the majority of patients needing a dose reduction or dose interruption. Evidence Rating Level: 2 (Good) Study Rundown: The use of anti-PD-1 or anti-PD-L1 agents has become ....

Rating Level , Hif 2α Inhibitor , Renal Cell Carcinoma , Chronic Disease ,

Preexisting heart failure associated with lower use of anthracyclines and chemotherapy

1. In this longitudinal cohort study of 30 728 patients with diffuse large-B-cell lymphoma, preexisting heart failure at lymphoma diagnosis was present in 4266 patients and associated with lower anthracyclines use. 2. At one year, lymphoma mortality was 41.8% in patients with preexisting heart failure and 29.6% in patients without preexisting heart failure. Evidence Rating ....

Rating Level , End Results , Diffuse Largeb Cell Lymphoma , Heart Failure , Chronic Disease ,

Program Cut Cancer Diagnostic Time by Over 62% for Underserved Populations

Colocating cancer diagnostic services in in community health centers serving historically marginalized populations resulted in reduced time to a diagnosis. ....

United States , Dana Farber Cancer Institute , Health Center , Federally Qualified Health Center , Farber Cancer Institute ,

Disulfiram is not effective as an adjunctive therapy to standard chemotherapy for glioblastoma

1. Adding disulfiram and copper to standard alkylating chemotherapy for glioblastoma (GB) was not associated with improved survival or quality of life, and was associated with increased adverse events. Evidence Rating Level: 1 (Excellent) New systemic treatments for glioblastoma (GB) have not been well-established since the arrival of temozolomide. However, disulfiram with or without copper ....

Rating Level , Chronic Disease ,

Jurassic Park star Sam Neill is 'absolutely fine' after his cancer battle

Sam Neill has reassured fans he s doing well after beating "a ferocious type of aggressive" non-Hodgkin lymphoma. ....

Sam Neill , Annette Bening , Jurassic Park , Didi Ever Tell You , Sky News , Im Sam Neill , Apples Never Fall ,