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Optimizing Subtyping-Based Therapy in Triple-Negative Breast Cancer

1. The median progression-free survival was improved with the pooled subtyping-based therapy group compared to the control group (11.3 months vs 5.8 months with an HR 0.44). 2. Grade 3-4 adverse events occurred in 57% of the subtyping-based group and 31% in the control group with the most common being neutropenia, anemia, and increased alanine ....

Rating Level , Transcriptomic Landscape , Triple Negative Breast Cancers , Advanced Breast Cancer , Precision Oncology , Triple Negative Breast Cancer , Chronic Disease ,

Mobile application communication may improve palliative care needs met in critically ill patients

1. Families randomized to having access to a mobile application that allowed them to communicate needs with intensive care unit (ICU) physicians were found to have reduced unmet palliative care needs compared to usual care. 2. White families were observed to benefit more from the intervention than Black families as measured by the Needs at ....

North Carolina , United States , End Of Life Screening Tool , Level Rating , Critical Care , Critically Ill , End Of Life Care , Palliative Care , Chronic Disease ,

Computed Tomography coronary calcium scores may predict risk of cardiovascular events in cancer patients

1. Despite lower prevalence of traditional cardiovascular risk factors, cancer patients were observed to have similar cardiovascular disease (CVD) events ot non-cancer counterparts. 2. Coronary artery calcium score (CACS) were well correlated with CVD risk in cancer patients suggesting a potential role as a targeted screening tool. Evidence Level Rating: 2 (Good) To date, cancer ....

Level Rating , Cardiovascular Disease , Chronic Disease , Imaging And Intervention ,